Oral administration of high doses of pseudoephedrine (PSE) hydrochloride accelerates the onset of CNS oxygen toxicity (CNS‐OT) seizures in rats exposed to hyperbaric oxygen (HBO) at 5 atmospheres absolute (ATA)
نویسندگان
چکیده
منابع مشابه
Female rats are more susceptible to central nervous system oxygen toxicity than male rats
Abstract Tonic-clonic seizures typify central nervous system oxygen toxicity (CNS-OT) in humans and animals exposed to high levels of oxygen, as are encountered during scuba diving. We previously demonstrated that high doses of pseudoephedrine (PSE) decrease the latency to seizure (LS) for CNS-OT in young male rats. This study investigated whether female rats respond similarly to PSE and hyperb...
متن کاملHyperbaric oxygen exposures at 3 and 4 atmospheres absolute pressure for experimental gas gangrene: succinate protection against oxygen toxicity.
The concurrent effect of succinate administration to protect against oxygen toxicity and of hyperbaric oxygen (HBO) exposures to treat model gas gangrene in mice was tested to determine whether succinate would interfere with the therapeutic efficacy of HBO. HBO (seven 90-min exposures) at 3 atmospheres absolute pressure (ATA) had been shown to reduce significantly the mortality of mice injected...
متن کاملCentral Nervous System Oxygen Toxicity and Hyperbaric Oxygen Seizures.
INTRODUCTION The use of hyperbaric oxygen (O2) as a therapeutic agent carries with it the risk of central nervous system (CNS) O2 toxicity. METHODS To further the understanding of this risk and the nature of its molecular mechanism, a review was conducted on the literature from various fields. RESULTS Numerous physiological changes are produced by increased partial pressures of oxygen (Po2)...
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In hyperbaric oxygen (HBO(2)) at or above 3 atmospheres absolute (ATA), autonomic pathways link central nervous system (CNS) oxygen toxicity to pulmonary damage, possibly through a paradoxical and poorly characterized relationship between central nitric oxide production and sympathetic outflow. To investigate this possibility, we assessed sympathetic discharges, catecholamine release, cardiopul...
متن کاملthe impact of musical texts on the text recall of young learners of english in isfahan junior high schools
abstract although music possesses some kind of power and using it has been welcome by many students in language classrooms, it seems that they take a non-serious image of the lesson while listening to songs and they may think that it is a matter of fun. the main objective of the present study was to investigate whether learning a foreign language through musical texts (songs) can have an impac...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2013
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.27.1_supplement.933.4